Journal of Biomedical Science

Top Cited Research Papers 2025

Impact of large language model (ChatGPT) in healthcare: an umbrella review and evidence synthesis

Usman Iqbal, Afifa Tanweer, Annisa Ristya Rahmanti, David Greenfield, Leon Tsung-Ju Lee and Yu-Chuan Jack Li

Journal of Biomedical Science 2025 32:45 | Published on: 7 May 2025

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Fusobacterium nucleatum promotes colorectal cancer liver metastasis via miR-5692a/IL-8 axis by inducing epithelial-mesenchymal transition

Yulong Yu, Han Yin, Bili Wu, Weiheng Zhao, Yuan Wang, Aifeina Aili, Mu Yang, Qianqian Yu and Xianglin Yuan

Journal of Biomedical Science 2025 32:5 | Published on: 6 January 2025

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Mitophagy is required to protect against excessive skeletal muscle atrophy following hindlimb immobilization

Rahman, Fasih A.; Graham, Mackenzie Q.; Adam, Amanda M.; Juracic, Emma S.; Tupling, A. Russell; Quadrilatero, Joe

Journal of Biomedical Science 2025 32:29 | Published on: 18 February 2025

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miR-200c inhibition and catalase accelerate diabetic wound healing

D'Agostino, Marco; Sileno, Sara; Lulli, Daniela; De Luca, Naomi; Scarponi, Claudia; Teson, Massimo; Torcinaro, Alessio; De Santa, Francesca; Cirielli, Corrado; Furgiuele, Sergio; Morrell, Chris H.; Dellambra, Elena; Odorisio, Teresa; Lakatta, Edward G.; Avitabile, Daniele; Capogrossi, M. C.; Magenta, Alessandra

Journal of Biomedical Science 2025 32:21 | Published on: 14 February 2025

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Keratin 6A promotes skin inflammation through JAK1-STAT3 activation in keratinocytes

Chen, Mengting; Wang, Yaling; Wang, Mei; Xu, San; Tan, Zixin; Cai, Yisheng; Xiao, Xin; Wang, Ben; Deng, Zhili; Li, Ji

Journal of Biomedical Science 2025 32:47 | Published on: 09 May 2025

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Multifunctional hyaluronic acid-based biomimetic/pH-responsive hybrid nanostructured lipid carriers for treating bacterial sepsis

Elhassan, Eman; Omolo, Calvin A.; Gafar, Mohammed A.; Ismail, Eman A.; Ibrahim, Usri H.; Khan, Rene; Lesouhaitier, Mathieu; Kubes, Paul; Govender, Thirumala

Journal of Biomedical Science 2025 32:19 | Published on: 11 February 2025

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IL-19 as a promising theranostic target to reprogram the glioblastoma immunosuppressive microenvironment

Lee, Gilbert Aaron; Hsu, Justin Bo-Kai; Chang, Yu-Wei; Hsieh, Li-Chun; Li, Yi-Tien; Wu, Ying Chieh; Chu, Cheng-Ying; Chiang, Yung-Hsiao; Guo, Wan-Yuo; Wu, Chih-Chun; Chen, Liang-Wei; Kao, Hung-Wen; Lin, Wan-Li; Tseng, Li-Wen; Weng, Ting-Wei; Kuo, Duen-Pang; Cheng, Sho-Jen; Chen, Yung-Chieh; Huang, Shiu-Wen; Kung, Hsing-Jien; Chen, Cheng-Yu

Journal of Biomedical Science 2025 32:34 | Published on: 08 March 2025

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Blocking the SIRP�\-CD47 axis promotes macrophage phagocytosis of exosomes derived from visceral adipose tissue and improves inflammation and metabolism in mice

Lin, Yun-kai; Pan, Yu-fei; Jiang, Tian-yi; Chen, Yi-bin; Shang, Tai-yu; Xu, Meng-you; Feng, Hui-bo; Ma, Yun-han; Tan, Ye-xiong; Wang, Hong-yang; Dong, Li-wei

Journal of Biomedical Science 2025 32:31 | Published on: 28 February 2025

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miR-193b-3p suppresses lung cancer cell migration and invasion through PRNP targeting

Ho, Hsiang-Ling; Lin, Shin-Chih; Chiang, Chao-Wei; Lin, Ching; Liu, Che-Wei; Yeh, Yi-Chen; Chen, Mei-Yu; Chou, Teh-Ying

Journal of Biomedical Science 2025 32:28 | Published on: 20 February 2025

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Cardiac-specific overexpression of PRMT5 exacerbates pressure overload-induced hypertrophy and heart failure

Katanasaka, Yasufumi; Sunagawa, Yoichi; Sakurai, Ryoga; Tojima, Mikuto; Naruta, Ryuya; Hojo, Yuya; Kawase, Yuto; Hamabe-Horiike, Toshihide; Mori, Kiyoshi; Hasegawa, Koji; Morimoto, Tatsuya

Journal of Biomedical Science 2025 32:61 | Published on: 06 July 2025

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Top Cited Research Papers 2024

Engineered extracellular vesicles carrying let-7a-5p for alleviating inflammation in acute lung injury

Chen, Sin-Yu; Chen, Yi-Ling; Li, Po-Chen; Cheng, Tai-Shan; Chu, Yeh-Shiu; Shen, Yi-Shan; Chen, Hsin-Tung; Tsai, Wei-Ni; Huang, Chien-Ling; Sieber, Martin; Yeh, Yuan-Chieh; Liu, Hsiao-Sheng; Chiang, Chi-Ling; Chang, Chih-Hung; Lee, Andrew S.; Tseng, Yen-Han; Lee, Ly James; Liao, Hsiu-Jung; Yip, Hon-Kan; Huang, Chi-Ying F.

Journal of Biomedical Science 2024 31:30 | Published on: 19 March 2024

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Exploring the relationship between metabolism and immune microenvironment in osteosarcoma based on metabolic pathways

Wu, Changwu; Tan, Jun; Shen, Hong; Deng, Chao; Kleber, Christian; Osterhoff, Georg; Schopow, Nikolas

Journal of Biomedical Science 2024 31:4 | Published on: 12 January 2024

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Inactivation of pentraxin 3 suppresses M2-like macrophage activity and immunosuppression in colon cancer

Chen, Feng-Wei; Wu, Yung-Ling; Cheng, Chao-Chun; Hsiao, Yu-Wei; Chi, Jhih-Ying; Hung, Liang-Yi; Chang, Chih-Peng; Lai, Ming-Derg; Wang, Ju-Ming

Journal of Biomedical Science 2024 31:10 | Published on: 20 January 2024

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Neuroprotective effects of intranasal extracellular vesicles from human platelet concentrates supernatants in traumatic brain injury and Parkinson's disease models

Delila, Liling; Nebie, Ouada; Le, Nhi Thao Ngoc; Timmerman, Kelly; Lee, Deng-Yao; Wu, Yu-Wen; Chou, Ming-Li; Buee, Luc; Chou, Szu-Yi; Blum, David; Devos, David; Burnouf, Thierry

Journal of Biomedical Science 2024 31:87 | Published on: 05 September 2024

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Hesperetin activates CISD2 to attenuate senescence in human keratinocytes from an older person and rejuvenates naturally aged skin in mice

Shen, Zhao-Qing; Chang, Cheng-Yen; Yeh, Chi-Hsiao; Lu, Chung-Kuang; Hung, Hao-Chih; Wang, Tai-Wen; Wu, Kuan-Sheng; Tung, Chien-Yi; Tsai, Ting-Fen

Journal of Biomedical Science 2024 31:15 | Published on: 23 January 2024

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Attenuating mitochondrial dysfunction and morphological disruption with PT320 delays dopamine degeneration in MitoPark mice

Wang, Vicki; Tseng, Kuan-Yin; Kuo, Tung-Tai; Huang, Eagle Yi-Kung; Lan, Kuo-Lun; Chen, Zi-Rong; Ma, Kuo-Hsing; Greig, Nigel H.; Jung, Jin; Choi, Ho-, II; Olson, Lars; Hoffer, Barry J.; Chen, Yuan-Hao

Journal of Biomedical Science 2024 31:38 | Published on: 17 April 2024

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Adipocyte pyroptosis occurs in omental tumor microenvironment and is associated with chemoresistance of ovarian cancer

Lin, Chang-Ni; Liang, Yu-Ling; Tsai, Hsing-Fen; Wu, Pei-Ying; Huang, Lan-Yin; Lin, Yu-Han; Kang, Chieh-Yi; Yao, Chao-Ling; Shen, Meng-Ru; Hsu, Keng-Fu

Journal of Biomedical Science 2024 31:62 | Published on: 11 June 2024

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Plectin plays a role in the migration and volume regulation of astrocytes: a potential biomarker of glioblastoma

Zugec, Maja; Furlani, Borut; Castanon, Maria J.; Rituper, Bostjan; Fischer, Irmgard; Broggi, Giuseppe; Caltabiano, Rosario; Barbagallo, Giuseppe M. V.; Di Rosa, Michelino; Tibullo, Daniele; Parenti, Rosalba; Vicario, Nunzio; Simcic, Sasa; Pozo Devoto, Victorio Martin; Stokin, Gorazd B.; Wiche, Gerhard; Jorgacevski, Jernej; Zorec, Robert; Potokar, Maja

Journal of Biomedical Science 2024 31:14 | Published on: 23 January 2024

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A G-quadruplex-binding platinum complex induces cancer mitochondrial dysfunction through dual-targeting mitochondrial and nuclear G4 enriched genome

Kuang, Keli; Li, Chunyan; Maksut, Fatlinda; Ghosh, Deepanjan; Vinck, Robin; Wang, Maolin; Poupon, Joel; Xiang, Run; Li, Wen; Li, Fei; Wang, Zhu; Du, Junrong; Teulade-Fichou, Marie-Paule; Gasser, Gilles; Bombard, Sophie; Jia, Tao

Journal of Biomedical Science 2024 31:50 | Published on: 13 May 2024

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TEM1/endosialin/CD248 promotes pathologic scarring and TGF-�] activity through its receptor stability in dermal fibroblasts

Hong, Yi-Kai; Lin, Yu-Chen; Cheng, Tsung-Lin; Lai, Chao-Han; Chang, Yi-Han; Huang, Yu-Lun; Hung, Chia-Yi; Wu, Chen-Han; Hung, Kuo-Shu; Ku, Ya-Chu; Ho, Yen-Ting; Tang, Ming-Jer; Lin, Shu-Wha; Shi, Guey-Yueh; Mcgrath, John A.; Wu, Hua-Lin; Hsu, Chao-Kai

Journal of Biomedical Science 2024 31:12 | Published on: 23 January 2024

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